25122-41-2
25122-41-2
Chemical Structure
Betamethasone impurity 5
- CAS No.: 25122-41-2
- Formula:C22H28ClFO4
- Molecular Weight:410.91
InChIKey: FCSHDIVRCWTZOX-DVTGEIKXSA-N
SMILES: F[C@@]12[C@](CCC([C@@]2(C=C3)C)=CC3=O)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](O)([C@H](C4)C)C(CCl)=O)C
Biological Activity: Betamethasone impurity 5 is an impurity of Betamethasone.
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Betamethasone impurity 5 | Betamethasone impurity 5 is an impurity of Betamethasone. | |||||||||||||||||||||
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Clobetasol | Clobetasol is a glucocorticoid and Smoothened agonist that can cross the blood-brain barrier. Clobetasol induces Smo-dependent activation of the Shh signaling pathway and nuclear translocation of Gli1. Clobetasol promotes remyelination and reduces myelin loss in lesions of neuromyelitis optica (NMO). Clobetasol may cause adrenal suppression, cushingoid appearance, and local adverse reactions including dysgeusia, xerostomia, and gastroesophageal burning. Clobetasol can be used in research related to neurodegenerative diseases, oral lichen planus, mucous membrane pemphigoid, and neuromyelitis optica. | |||||||||||||||||||||
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Keywords
