2525173-96-8
2525173-96-8
Chemical Structure
HIV-1 protease-IN-5
- CAS No.: 2525173-96-8
- Formula:C27H29F3N2O7S
- Molecular Weight:582.59
IUPAC Name: 3,4-dihydroxy-N-((2S,3R)-3-hydroxy-4-((N-((R)-2-hydroxypropyl)-4-(trifluoromethyl)phenyl)sulfonamido)-1-phenylbutan-2-yl)benzamide
InChIKey: QZWKKTZPHACWGC-VEDVITAVSA-N
SMILES: C[C@H](CN(S(=O)(C1=CC=C(C=C1)C(F)(F)F)=O)C[C@H]([C@@H](NC(C2=CC(O)=C(C=C2)O)=O)CC3=CC=CC=C3)O)O
Biological Activity: HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants[1].
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HIV-1 protease-IN-5 | HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC50 of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants. | |||||||||||||||||||||
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References
Keywords
