2543763-00-2
Chemical Structure
EGFR-IN-123
- CAS No.: 2543763-00-2
- Formula:C24H27F3N6O
- Molecular Weight:472.51
InChIKey: JWHOTQWEKXOWHS-UHFFFAOYSA-N
SMILES: COC1=CC=CC(NC2=CC(NC3=CC=C(CN4CCN(C)CC4)C(C(F)(F)F)=C3)=NC=N2)=C1
Biological Activity: EGFR-IN-123 (compound D06) is a potent EGFR inhibitor. EGFR-IN-123 inhibits PC-9G, A549, A431 and HCT116 cells with IC50s of 0.74, 1.36, 1.20 and 2.53 μM, respectively[1].
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EGFR-IN-123 | EGFR-IN-123 (compound D06) is a potent EGFR inhibitor. EGFR-IN-123 inhibits PC-9G, A549, A431 and HCT116 cells with IC50s of 0.74, 1.36, 1.20 and 2.53 μM, respectively. | |||||||||||||||||||||
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Keywords