256411-32-2
256411-32-2
Chemical Structure
Belotecan
Synonym(s): CKD-602 free base
- CAS No.: 256411-32-2
- Formula:C25H27N3O4
- Molecular Weight:433.50
IUPAC Name: (S)-4-ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
InChIKey: LNHWXBUNXOXMRL-VWLOTQADSA-N
SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CCNC(C)C)C5=CC=CC=C5N=C4C3=C2)=O
Biological Activity: Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer[1].
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Belotecan | 99.86% | Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer. | ||||||||||||||||||||
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Belotecan (Standard) | ≥98% | Belotecan (Standard) is the analytical standard of Belotecan. This product is intended for research and analytical applications. Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-13566ABelotecan hydrochloride -
Similarity Score 0.88
HY-1591627-(2-Aminoethyl)camptothecin -
Similarity Score 0.87
HY-14812Karenitecin -
Similarity Score 0.86
HY-N21087-Ethylcamptothecin -
Similarity Score 0.85
HY-148185T01-1 -
Similarity Score 0.82
HY-W7402217-Ethylcamptothecin-d3-1 -
Similarity Score 0.82
HY-13566ASBelotecan-d7 hydrochloride -
Similarity Score 0.80
HY-174151XSJ110 -
Similarity Score 0.78
HY-14821Namitecan -
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