259143-19-6
Chemical Structure
N-(α-Linolenoyl) tyrosine
Synonym(s): NLT
- CAS No.: 259143-19-6
- Formula:C27H39NO4
- Molecular Weight:441.60
IUPAC Name: methyl 1-((tert-butoxycarbonyl)amino)-3-formylcyclobutane-1-carboxylate
InChIKey: DEQLZTQITSWABQ-GMOGWPNXSA-N
SMILES: CC/C=C\C/C=C\C/C=C\CCCCCCCC(N[C@H](C(O)=O)CC1=CC=C(C=C1)O)=O
Biological Activity: N-(α-Linolenoyl) tyrosine (NLT) is a dopaminergic agonist capable of crossing the blood-brain barrier. N-(α-Linolenoyl) tyrosine increases the level, turnover rate and release amount of dopamine in the striatum. N-(α-Linolenoyl) tyrosine modulates rotational behavior in a rat model with unilateral striatal injury and alleviates excessive blinking symptoms in models induced by dopamine-depleting agents. N-(α-Linolenoyl) tyrosine can be used for research on Parkinson's disease and idiopathic blepharospasm[1].
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N-(α-Linolenoyl) tyrosine | 98.98% | N-(α-Linolenoyl) tyrosine (NLT) is a dopaminergic agonist capable of crossing the blood-brain barrier. N-(α-Linolenoyl) tyrosine increases the level, turnover rate and release amount of dopamine in the striatum. N-(α-Linolenoyl) tyrosine modulates rotational behavior in a rat model with unilateral striatal injury and alleviates excessive blinking symptoms in models induced by dopamine-depleting agents. N-(α-Linolenoyl) tyrosine can be used for research on Parkinson's disease and idiopathic blepharospasm. | ||||||||||||||||||||
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