2597167-25-2
2597167-25-2
Chemical Structure
Thalidomide-O-amido-PEG1-azide
- CAS No.: 2597167-25-2
- Formula:C19H20N6O7
- Molecular Weight:444.40
IUPAC Name: N-(2-(2-azidoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
InChIKey: UEBWOTMORCLMHG-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Biological Activity: Thalidomide-O-amido-PEG1-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG1-azide can be linked to a target protein ligand via a linker to form a PROTAC.
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Thalidomide-O-amido-PEG1-azide | Thalidomide-O-amido-PEG1-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG1-azide can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
