2626988-86-9
2626988-86-9
Chemical Structure
IRAK4-IN-27
- CAS No.: 2626988-86-9
- Formula:C23H22N6O3
- Molecular Weight:430.46
InChIKey: OYRHXSCBISAPLC-UHFFFAOYSA-N
SMILES: O=C(C1=COC(C2=CC(N)=NC=C2)=N1)NC3=C(C4=CN(C)N=C4)C=C(OC(C)(C)C5)C5=C3
Biological Activity: IRAK4-IN-27 (Compound 22) is a potent, selective inhibitor of IRAK4, with IC50 of 8.7 nM. IRAK4-IN-27 inhibits cell growth, and promotes apoptosis in MYD88 L265P diffuse large B-cell lymphoma (DLBCL) cell line. IRAK4-IN-27 can be used for DLBCL study[1].
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IRAK4-IN-27 | IRAK4-IN-27 (Compound 22) is a potent, selective inhibitor of IRAK4, with IC50 of 8.7 nM. IRAK4-IN-27 inhibits cell growth, and promotes apoptosis in MYD88 L265P diffuse large B-cell lymphoma (DLBCL) cell line. IRAK4-IN-27 can be used for DLBCL study. | |||||||||||||||||||||
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