263754-93-4
Chemical Structure
LA-419
- CAS No.: 263754-93-4
- Formula:C8H11NO6S
- Molecular Weight:249.24
IUPAC Name: S-((3S,3aS,6R,6aS)-6-(nitrooxy)hexahydrofuro[3,2-b]furan-3-yl) ethanethioate
InChIKey: BXZDULYKEZVEEK-ULAWRXDQSA-N
SMILES: [H][C@]12[C@]([C@@H](SC(C)=O)CO2)([H])OC[C@H]1O[N+]([O-])=O
Biological Activity: LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease[1].
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LA-419 | LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease. | |||||||||||||||||||||
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Keywords
