2643356-08-3
2643356-08-3
Chemical Structure
NMDA receptor antagonist-12
- CAS. Nr.: 2643356-08-3
- Formula:C18H17F3N2O3
- Molecular Weight:366.33
InChIKey: QSRWOOQUHNIYEQ-HZMBPMFUSA-N
SMILES: C[C@@H]([C@H](CC1=O)O)N1CC2=CN=C(OC3=C(C=C(C=C3)C(F)F)F)C=C2
Biological Activity: NMDA receptor antagonist-12 (Example 17) is an antagonist of NMDA receptors containing the NR2B subunit. NMDA receptor antagonist-12 exerts antagonistic effects on NMDA receptors containing the NR2B subunit and blocks the intracellular Ca2+ influx mediated by these receptors. NMDA receptor antagonist-12 can be used in research related to diseases such as depression, bipolar disorder, migraine, and pain[1].
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NMDA receptor antagonist-12 | NMDA receptor antagonist-12 (Example 17) is an antagonist of NMDA receptors containing the NR2B subunit. NMDA receptor antagonist-12 exerts antagonistic effects on NMDA receptors containing the NR2B subunit and blocks the intracellular Ca2+ influx mediated by these receptors. NMDA receptor antagonist-12 can be used in research related to diseases such as depression, bipolar disorder, migraine, and pain. | |||||||||||||||||||||
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