2673323-38-9
2673323-38-9
Chemical Structure
CAII-IN-16
- CAS No.: 2673323-38-9
- Formula:C25H24FN5O10S
- Molecular Weight:605.55
InChIKey: RYMCEUDYCFTUQN-QMDPOKHVSA-N
SMILES: CC1=C(C(OC2=C1C=CC(OCC3=CN(N=N3)[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(NC5=CC=C(S(=O)(N)=O)C=C5)=O)O4)=C2)=O)F
Biological Activity: CAII-IN-16 is a selective inhibitor of carbonic anhydrase II (CA II), with an IC50 of 0.5 nM against hCA II. CAII-IN-16 exhibits excellent intraocular pressure-lowering activity in a rabbit glaucoma animal model. CAII-IN-16 can be used for the research of glaucoma[1].
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CAII-IN-16 | CAII-IN-16 is a selective inhibitor of carbonic anhydrase II (CA II), with an IC50 of 0.5 nM against hCA II. CAII-IN-16 exhibits excellent intraocular pressure-lowering activity in a rabbit glaucoma animal model. CAII-IN-16 can be used for the research of glaucoma. | |||||||||||||||||||||
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References
Keywords
