2678601-07-3
Chemical Structure
AChE-IN-105
- CAS No.: 2678601-07-3
- Formula:C26H22O9
- Molecular Weight:478.45
InChIKey: XNSFJGCTDFIGNW-HNNXBMFYSA-N
SMILES: O=C1C2=C(O)C(O)=C(O)C([C@@H](CC(OC)=O)C3=CC(O)=C(OC)C=C3)=C2OC(C4=CC=CC=C4)=C1
Biological Activity: AChE-IN-105 (Compound C5) is a potent, mixed AChE inhibitor with an IC50 of 5.02 μM. AChE-IN-105 scavenges ROS, decreases Hydrogen peroxide-induced Caspase-3 activation, reduces activity of the Nrf2-ARE pathway. AChE-IN-105 prevents memory impairments in the Scopolamine (HY-N0296)-induced cognitive dysfunction zebrafish model. AChE-IN-105 has potent antioxidant activity. AChE-IN-105 can be used in the research of Alzheimer's disease[1].
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AChE-IN-105 | AChE-IN-105 (Compound C5) is a potent, mixed AChE inhibitor with an IC50 of 5.02 μM. AChE-IN-105 scavenges ROS, decreases Hydrogen peroxide-induced Caspase-3 activation, reduces activity of the Nrf2-ARE pathway. AChE-IN-105 prevents memory impairments in the Scopolamine (HY-N0296)-induced cognitive dysfunction zebrafish model. AChE-IN-105 has potent antioxidant activity. AChE-IN-105 can be used in the research of Alzheimer's disease. | |||||||||||||||||||||
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