2742707-36-2
Chemical Structure
AChE-IN-19
- CAS. Nr.: 2742707-36-2
- Formula:C30H33NO7
- Molecular Weight:519.59
IUPAC Name: 5-methoxy-2-(3,4,5-trimethoxyphenyl)chroman-7-yl (E)-3-(4-(dimethylamino)phenyl)acrylate
InChIKey: CWEDIQHOXNMLQK-NTEUORMPSA-N
SMILES: O=C(OC1=CC(OC)=C2CCC(C3=CC(OC)=C(OC)C(OC)=C3)OC2=C1)/C=C/C4=CC=C(N(C)C)C=C4
Biological Activity: AChE-IN-19 (compound A15) is a highly potent AChE inhibitor with an IC50 value of 0.56 μM, also inhibits Aβ aggregation. AChE-IN-19 has potent neuroprotective activities and nearly no toxicity on SH-SY5Y cells. AChE-IN-19 can be used for researching Alzheimer's disease[1].
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AChE-IN-19 | AChE-IN-19 (compound A15) is a highly potent AChE inhibitor with an IC50 value of 0.56 μM, also inhibits Aβ aggregation. AChE-IN-19 has potent neuroprotective activities and nearly no toxicity on SH-SY5Y cells. AChE-IN-19 can be used for researching Alzheimer's disease. | |||||||||||||||||||||
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Keywords
