2745723-90-2

STING agonist-8 Chemical Structure
2745723-90-2

Chemical Structure

STING agonist-8

  • CAS No.: 2745723-90-2
  • Formula:C41H46N14O4
  • Molecular Weight:798.90

IUPAC Name: (E)-8-(3-(azetidin-3-yl)propoxy)-9-(4-(6-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-3H-imidazo[4,5-b]pyridin-3-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-9H-pyrimido[4,5-b]indole-6-carboxamide

InChIKey: HXLLQIDDTRZWGW-BQYQJAHWSA-N

SMILES: O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCC6CNC6)C=C(C(N)=O)C=C5C7=CN=C(C8=CC(C)=NN8CC)N=C74

Biological Activity: STING agonist-8 is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells (WO2021239068A1, compound 5-AB)[1].

Cat. No. Product Name Purity Description Pricing
HY-144168 		STING agonist-8 STING agonist-8 is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells (WO2021239068A1, compound 5-AB).
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