2747-05-9
2747-05-9
Chemical Structure
7-Acetoxy-4-methylcoumarin
Synonym(s): 4-Methylumbelliferyl acetate
- CAS No.: 2747-05-9
- Formula:C12H10O4
- Molecular Weight:218.21
IUPAC Name: 4-methyl-2-oxo-2H-chromen-7-yl acetate
InChIKey: HXVZGASCDAGAPS-UHFFFAOYSA-N
SMILES: O=C1C=C(C)C2=CC=C(OC(C)=O)C=C2O1
Biological Activity: 7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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7-Acetoxy-4-methylcoumarin | 98.65% | 7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition. | ||||||||||||||||||||
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References
- [1]. Feuer, G, et al. Induction of drug-metabolizing enzymes of rat liver by derivatives of coumarin. Canadian Journal of Physiology and Pharmacology, 48(4), 232–240.
- [2]. Raj HG, et al. Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom. Bioorg Med Chem. 2001 May;9(5):1085-9. [Content Brief]
