2760849-95-2
2760849-95-2
Chemical Structure
CRBN ligand-749
- CAS No.: 2760849-95-2
- Formula:C12H10BrFN4O2
- Molecular Weight:341.14
IUPAC Name: 1-(6-bromo-7-fluoro-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: DGACDRNUPQHSMA-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C2=NN(C=3C(F)=C(Br)C=CC23)C
Biological Activity: CRBN ligand-749 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-749 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-749 | CRBN ligand-749 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-749 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
