2768426-49-7
2768426-49-7
Chemical Structure
FDW028
- CAS No.: 2768426-49-7
- Formula:C22H24N6O
- Molecular Weight:388.47
InChIKey: LJEVZCFIZASGBF-UHFFFAOYSA-N
SMILES: OC1=CC(CNCC2=CC=CC=C2)=NC3=NC(NCC4=CC=C(CC)C=C4)=NN31
Biological Activity: FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FDW028 | 99.41% | FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.50
HY-179257p97-IN-2 -
Similarity Score 0.50
HY-15945DBeQ -
Similarity Score 0.49
HY-185266Rev1-CT/RIR PPI-IN-2 -
Similarity Score 0.49
HY-169704Ogerin analogue 1 -
Similarity Score 0.48
HY-170236nNOS-IN-5 -
Similarity Score 0.48
HY-113846ACMP-5 dihydrochloride -
Similarity Score 0.48
HY-113846CMP-5 hydrochloride -
Similarity Score 0.47
HY-110279Ogerin -
Similarity Score 0.47
HY-1478105-HT7 receptor ligand 1 -
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