2781918-27-0
2781918-27-0
Chemical Structure
AKT-IN-14 free base
- CAS No.: 2781918-27-0
- Formula:C22H21BrF2N4OS
- Molecular Weight:507.39
InChIKey: CEEODNJYPPDYNU-SCLBCKFNSA-N
SMILES: BrC1=C2C3=C(CCCN2N=C1)SC(C(N[C@H]4[C@H](C5=CC(F)=C(C=C5)F)CCNC4)=O)=C3
Biological Activity: AKT-IN-14 (Example 2) free baseis a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. AKT-IN-14 free basecan be used in cancer research[1].
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AKT-IN-14 free base | AKT-IN-14 (Example 2) free baseis a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. AKT-IN-14 free basecan be used in cancer research. | |||||||||||||||||||||
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References
Keywords
