2789678-92-6
2789678-92-6
Chemical Structure
SJ10542
- CAS No.: 2789678-92-6
- Formula:C41H46N12O5S
- Molecular Weight:818.95
IUPAC Name: 4-bromo-2,2-dimethylindoline
InChIKey: WBEBZVDAHMXWJN-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC2=NC(NC=C3)=C3C(C4=CN(C5(CN(S(=O)(CC)=O)C5)CC#N)N=C4)=N2)C=C1)NCCCN(CC6)CCN6C7=CC=C(C=C7)C8C(NC(CC8)=O)=O
Biological Activity: SJ10542 is a potent and selective JAK2/3 PROTAC degrader, with DC50 values of 14 nM and 11 nM against JAK2 and JAK3, respectively. SJ10542 exhibits anti-tumor activity and can be used for research on acute lymphoblastic leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SJ10542 | 99.32% | SJ10542 is a potent and selective JAK2/3 PROTAC degrader, with DC50 values of 14 nM and 11 nM against JAK2 and JAK3, respectively. SJ10542 exhibits anti-tumor activity and can be used for research on acute lymphoblastic leukemia. | ||||||||||||||||||||
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References
Keywords
