2797619-65-7
Chemical Structure
Thalidomide-Propargyne-PEG2-COOH
- CAS No.: 2797619-65-7
- Formula:C21H20N2O8
- Molecular Weight:428.39
IUPAC Name: 3-(2-((3-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)prop-2-yn-1-yl)oxy)ethoxy)propanoic acid
InChIKey: KZTYSRQJBNPAOM-UHFFFAOYSA-N
SMILES: O=C1N(C2C(NC(CC2)=O)=O)C(C3=CC(C#CCOCCOCCC(O)=O)=CC=C31)=O
Biological Activity: Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Thalidomide-Propargyne-PEG2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Thalidomide-Propargyne-PEG2-COOH | 98.73% | Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Thalidomide-Propargyne-PEG2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
