2816102-69-7
2816102-69-7
Chemical Structure
sEH inhibitor-2
- CAS No.: 2816102-69-7
- Formula:C23H18N4O3
- Molecular Weight:398.41
IUPAC Name: 2-((4-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)phenyl)carbamoyl)benzoic acid
InChIKey: BCSKPQWWMRKHNG-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1C(NC2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=CC=C4)=O)O
Biological Activity: sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection[1].
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sEH inhibitor-2 | sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection. | |||||||||||||||||||||
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