2825567-97-1
Chemical Structure
Cathepsin C-IN-5
- CAS No.: 2825567-97-1
- Formula:C21H17ClN6OS
- Molecular Weight:436.92
IUPAC Name: N-(3-((5-chloro-2-((5-(thiophen-3-yl)pyridin-2-yl)amino)pyrimidin-4-yl)amino)phenyl)acetamide
InChIKey: CVEIEBFUSJRUSP-UHFFFAOYSA-N
SMILES: CC(NC1=CC=CC(NC2=C(C=NC(NC3=NC=C(C=C3)C4=CSC=C4)=N2)Cl)=C1)=O
Biological Activity: Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 µM, >5 µM, >5 µM, >5 µM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cathepsin C-IN-5 | 95.70% | Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 µM, >5 µM, >5 µM, >5 µM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity. | ||||||||||||||||||||
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Keywords
