2845151-86-0
2845151-86-0
Chemical Structure
Polfurmetinib
Synonym(s): MEK-IN-6
- CAS No.: 2845151-86-0
- Formula:C18H20FN3O4S
- Molecular Weight:393.43
IUPAC Name: 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione
InChIKey: TURWFFGYNJNSFK-UHFFFAOYSA-N
SMILES: O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC
Biological Activity: Polfurmetinib (MEK-IN-6) is a MEK inhibitor and inhibits ERK1/2 phosphorylation in A375 cells. Polfurmetinib can be used for cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Polfurmetinib | 98.28% | Polfurmetinib (MEK-IN-6) is a MEK inhibitor and inhibits ERK1/2 phosphorylation in A375 cells. Polfurmetinib can be used for cancer research. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-153445APolfurmetinib hydrate -
Similarity Score 0.55
HY-12058AZD8330 -
Similarity Score 0.50
HY-156625Nedometinib -
Similarity Score 0.47
HY-123883MK-0536 -
Similarity Score 0.46
HY-15202RBinimetinib (Standard) -
Similarity Score 0.46
HY-183674MEK-IN-10 -
Similarity Score 0.46
HY-15610GDC-0623 -
Similarity Score 0.45
HY-14719RO4987655 -
Similarity Score 0.45
HY-50706RSelumetinib (Standard) -
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