284661-73-0
Chemical Structure
DPC 684
- CAS. Nr.: 284661-73-0
- Formula:C35H48FN5O5S
- Molecular Weight:669.85
InChIKey: IXZYCIFRVZKVRJ-RKKDRKJOSA-N
SMILES: O=S(N(CC(C)C)C[C@@H](O)[C@@H](NC([C@H](C(C)(C)C)NC(CNCC1=CC(F)=CC=C1)=O)=O)CC2=CC=CC=C2)(C3=CC=C(C=C3)N)=O
Biological Activity: DPC 684 is a potent and selective HIV-1 protease inhibitor (IC90 = 5.7-40 nM, Ki = 0.021 nM). DPC 684 competitively inhibits HIV-1 protease and blocks viral polyprotein cleavage. DPC 684 has low protein binding and broad-spectrum inhibition against a variety of wild-type and mutant HIV-1 proteases. DPC 684 has low protein binding and broad-spectrum inhibition (IC90 = 1.9-6.3 nM). DPC 684 has research significance for HIV[1].
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DPC 684 | DPC 684 is a potent and selective HIV-1 protease inhibitor (IC90 = 5.7-40 nM, Ki = 0.021 nM). DPC 684 competitively inhibits HIV-1 protease and blocks viral polyprotein cleavage. DPC 684 has low protein binding and broad-spectrum inhibition against a variety of wild-type and mutant HIV-1 proteases. DPC 684 has low protein binding and broad-spectrum inhibition (IC90 = 1.9-6.3 nM). DPC 684 has research significance for HIV. | |||||||||||||||||||||
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Keywords
