2848620-87-9
2848620-87-9
Chemical Structure
HSD17B13-IN-93
- CAS No.: 2848620-87-9
- Formula:C19H12ClF4N3O3S
- Molecular Weight:473.83
InChIKey: DWGWVWCZBPKJDY-UHFFFAOYSA-N
SMILES: FC1=C(O)C(Cl)=CC(C(NC2=C(C(NCC3=CC=CC=C3C(F)(F)F)=O)SC=N2)=O)=C1
Biological Activity: HSD17B13-IN-93 (Compound 9) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value for estradiol that is greater than 0.1 μM and less than or equal to 0.5 μM. HSD17B13-IN-93 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-93 | HSD17B13-IN-93 (Compound 9) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value for estradiol that is greater than 0.1 μM and less than or equal to 0.5 μM. HSD17B13-IN-93 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
