1. Metabolic Enzyme/Protease
  2. 17β-HSD
  3. HSD17B13-IN-93

HSD17B13-IN-93 (Compound 9) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value for estradiol that is greater than 0.1 μM and less than or equal to 0.5 μM. HSD17B13-IN-93 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI).

For research use only. We do not sell to patients.

HSD17B13-IN-93 Chemical Structure

HSD17B13-IN-93 Chemical Structure

CAS No. : 2848620-87-9

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Description

HSD17B13-IN-93 (Compound 9) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value for estradiol that is greater than 0.1 μM and less than or equal to 0.5 μM. HSD17B13-IN-93 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].

Molecular Weight

473.83

Formula

C19H12ClF4N3O3S

CAS No.
SMILES

FC1=C(O)C(Cl)=CC(C(NC2=C(C(NCC3=CC=CC=C3C(F)(F)F)=O)SC=N2)=O)=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HSD17B13-IN-93 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HSD17B13-IN-93
Cat. No.:
HY-162219
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