2848620-90-4
Chemical Structure
HSD17B13-IN-94
- CAS No.: 2848620-90-4
- Formula:C21H20ClN3O4S
- Molecular Weight:445.92
InChIKey: RPFASOHQEXEPRA-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(NC2=C(C(NCCC3=C(OC)C=CC=C3)=O)N=C(C)S2)=O)C=C1Cl
Biological Activity: HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol (HY-B0141). HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI)[1].
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HSD17B13-IN-94 | HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol (HY-B0141). HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI). | |||||||||||||||||||||
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Keywords