2855087-10-2
2855087-10-2
Chemical Structure
CDK8-IN-5
- CAS No.: 2855087-10-2
- Formula:C26H22N2O4
- Molecular Weight:426.46
IUPAC Name: 5-hydroxy-2-phenyl-7-(4-(piperazine-1-carbonyl)phenyl)-4H-chromen-4-one
InChIKey: MVNMSJKQMNWECK-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)C2=CC(OC(C3=CC=CC=C3)=C4)=C(C(O)=C2)C4=O)N5CCNCC5
Biological Activity: CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease[1].
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CDK8-IN-5 | CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease. | |||||||||||||||||||||
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References
Keywords
