1. Cell Cycle/DNA Damage
  2. CDK
  3. CDK8-IN-5

CDK8-IN-5 

Cat. No.: HY-147527
Handling Instructions

CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease.

For research use only. We do not sell to patients.

CDK8-IN-5 Chemical Structure

CDK8-IN-5 Chemical Structure

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Description

CDK8-IN-5 is a potent CDK8 inhibitor with an IC50 of 72 nM. CDK8-IN-5 shows anti-inflammatory activities with 43% IL-10 enhancement rate. CDK8-IN-5 has the potential for the research of inflammatory bowel disease[1].

IC50 & Target[1]

CDK8

72 nM (IC50)

Molecular Weight

426.46

Formula

C26H22N2O4

SMILES

O=C(C1=CC=C(C=C1)C2=CC(OC(C3=CC=CC=C3)=C4)=C(C(O)=C2)C4=O)N5CCNCC5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
CDK8-IN-5
Cat. No.:
HY-147527
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