2866142-33-6
2866142-33-6
Chemical Structure
uPA-IN-1
- CAS No.: 2866142-33-6
- Formula:C19H16N2O5
- Molecular Weight:352.34
InChIKey: HQBGAYSIULYNQH-HNNXBMFYSA-N
SMILES: O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC(C3=CC=C(OCO4)C4=C3)=O
Biological Activity: uPA-IN-1 is a uPA inhibitor (IC50 = 0.546 μM). uPA-IN-1 induces G2/M cell cycle arrest, Apoptosis, and an increase in intracellular ROS, while upregulating the pro-apoptotic protein Bax and downregulating the anti-apoptotic protein Bcl-2. uPA-IN-1 can be used for cancer research[1].
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uPA-IN-1 | uPA-IN-1 is a uPA inhibitor (IC50 = 0.546 μM). uPA-IN-1 induces G2/M cell cycle arrest, Apoptosis, and an increase in intracellular ROS, while upregulating the pro-apoptotic protein Bax and downregulating the anti-apoptotic protein Bcl-2. uPA-IN-1 can be used for cancer research. | |||||||||||||||||||||
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