2867519-51-3
2867519-51-3
Chemical Structure
TMX-4140
- CAS No.: 2867519-51-3
- Formula:C25H20ClN5O
- Molecular Weight:441.91
IUPAC Name: 1-(5-((4-([1,1'-biphenyl]-3-yl)-5-chloropyrimidin-2-yl)amino)pyridin-3-yl)pyrrolidin-2-one
InChIKey: KNVNHPJZBGYCIW-UHFFFAOYSA-N
SMILES: ClC1=CN=C(N=C1C2=CC=CC(C3=CC=CC=C3)=C2)NC4=CC(N5CCCC5=O)=CN=C4
Biological Activity: TMX-4140 is a selective PIP4K2C inhibitor with a KD of 7.2 nM for PIP4K2C over PIP4K2B. TMX-4140 can be used for synthesis of PROTAC TMX-4153 (HY-153119)[1].
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TMX-4140 | TMX-4140 is a selective PIP4K2C inhibitor with a KD of 7.2 nM for PIP4K2C over PIP4K2B. TMX-4140 can be used for synthesis of PROTAC TMX-4153 (HY-153119). | |||||||||||||||||||||
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References
Keywords
