2890177-90-7
2890177-90-7
Chemical Structure
AcrB-IN-2
- CAS No.: 2890177-90-7
- Formula:C30H35NO6
- Molecular Weight:505.60
IUPAC Name: (7-(3-(4-methoxyphenoxy)propoxy)-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromen-5-yl)(morpholino)methanone
InChIKey: UWPJCMMNJWEMKM-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)OCCCOC2=CC=CC3=C2C=C(C4=C3OC(C)(CC4)C)C(N5CCOCC5)=O
Biological Activity: AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model[1].
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AcrB-IN-2 | AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model. | |||||||||||||||||||||
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References
Keywords
