289665-92-5
289665-92-5
Chemical Structure
Argadin
- CAS No.: 289665-92-5
- Formula:C29H42N10O9
- Molecular Weight:674.71
InChIKey: FOZYKTUSOWWQGR-QANWUKQVSA-N
SMILES: O=C([C@@H](NC([C@](CCC1)([H])N1C2=O)=O)C3)N([C@@H]3O)[C@H](C(N[C@H](C(N[C@H]2CCCNC(NC(C)=O)=N)=O)CCCC(O)=O)=O)CC4=CN=CN4
Biological Activity: Argadin is a cyclopentapeptide chitinase inhibitor. Argadin inhibits chitinase B (ChiB) with a Ki value of 20 nM. Argadin can be used for the research of fungicid and insecticid[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Argadin | 98.71% | Argadin is a cyclopentapeptide chitinase inhibitor. Argadin inhibits chitinase B (ChiB) with a Ki value of 20 nM. Argadin can be used for the research of fungicid and insecticid. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.58
HY-P0231AZP-531 -
Similarity Score 0.52
HY-P5035Cyclo(Gly-Arg-Gly-Glu-Ser-Pro) -
Similarity Score 0.51
HY-P1565Transdermal Peptide Disulfide -
Similarity Score 0.51
HY-P2274Argifin -
Similarity Score 0.51
HY-101402ACyclo(his-pro) TFA -
Similarity Score 0.51
HY-P5314OK2 -
Similarity Score 0.50
HY-P4907RGD Negative Control -
Similarity Score 0.50
HY-N13127Segetalin C -
Similarity Score 0.50
HY-P11424Cyclo(GRGDSPA) -
Explore the MedChemAI to find more analogs
References
- [1]. Jun Koseki, et al. Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket. Chem Pharm Bull (Tokyo). 2016;64(7):1031-5. [Content Brief]
- [2]. Hiroaki Gouda, et al. Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem. 2008 Apr 1;16(7):3565-79. [Content Brief]
