2897652-01-4
2897652-01-4
Chemical Structure
PPARγ modulator-2
- CAS No.: 2897652-01-4
- Formula:C26H21NO7S3Se
- Molecular Weight:634.60
SMILES: O=S1(C2=CC=C(C=C2)OS(C3=CC=C(C=C3)C)(=O)=O)=N[Se]C4=CC(OS(C5=CC=C(C=C5)C)(=O)=O)=CC=C41
Biological Activity: PPARγ modulator-2 (Compound (R)-2n) is the reversible modulator for PPARγ that inhibits PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. PPARγ modulator-2 reduces blood glucose, improves the glucose tolerance and insulin tolerance, and exhibits anti-diabetic efficacy in db/db mouse models[1].
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PPARγ modulator-2 | PPARγ modulator-2 (Compound (R)-2n) is the reversible modulator for PPARγ that inhibits PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. PPARγ modulator-2 reduces blood glucose, improves the glucose tolerance and insulin tolerance, and exhibits anti-diabetic efficacy in db/db mouse models. | |||||||||||||||||||||
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