2911580-96-4
2911580-96-4
Chemical Structure
Afimkibart (WT IgG1)
Synonym(s): PF-06480605 (WT IgG1); RVT-3101 (WT IgG1)
- CAS No.: 2911580-96-4
- Formula:N/A
- Molecular Weight:(146.54 kDa)
SMILES: [Afimkibart (WT IgG1)]
Biological Activity: Afimkibart (PF-06480605; RVT-3101) is a fully human monoclonal antibody that selectively inhibits trimeric tumor necrosis factor-like ligand 1A (TL1A). Afimkibart neutralizes active trimeric TL1A, blocks TL1A-induced signaling pathways. Afimkibart inhibits NF-κB activation and IFN-γ production. Afimkibart can be used for the research of inflammatory bowel disease[1].
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Afimkibart (WT IgG1) | 99.59% | Afimkibart (PF-06480605; RVT-3101) is a fully human monoclonal antibody that selectively inhibits trimeric tumor necrosis factor-like ligand 1A (TL1A). Afimkibart neutralizes active trimeric TL1A, blocks TL1A-induced signaling pathways. Afimkibart inhibits NF-κB activation and IFN-γ production. Afimkibart can be used for the research of inflammatory bowel disease. | ||||||||||||||||||||
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