2913151-46-7
2913151-46-7
Chemical Structure
ASM-IN-1
- CAS No.: 2913151-46-7
- Formula:C16H12BrN3O4
- Molecular Weight:390.19
IUPAC Name: 3-(4-((4-bromophenoxy)methyl)phenyl)-N-hydroxy-1,2,4-oxadiazole-5-carboxamide
InChIKey: YYAPAXZETRKZHT-UHFFFAOYSA-N
SMILES: BrC1=CC=C(OCC2=CC=C(C3=NOC(C(NO)=O)=N3)C=C2)C=C1
Biological Activity: ASM-IN-1 is a potent and orally active acid sphingomyelinase (ASM) inhibitor with an IC50 value of 1.5 µM. ASM-IN-1 reduces lipid plaques in the aortic arch and aorta and reduces plasma ceramide concentration and Ox-LDL levels. ASM-IN-1 shows antiatherosclerotic and anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASM-IN-1 | 98.65% | ASM-IN-1 is a potent and orally active acid sphingomyelinase (ASM) inhibitor with an IC50 value of 1.5 µM. ASM-IN-1 reduces lipid plaques in the aortic arch and aorta and reduces plasma ceramide concentration and Ox-LDL levels. ASM-IN-1 shows antiatherosclerotic and anti-inflammatory activity. | ||||||||||||||||||||
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