2923686-62-6
2923686-62-6
Chemical Structure
PROTAC PARP1 degrader-2
- CAS. Nr.: 2923686-62-6
- Formula:C38H37F2N9O6
- Molecular Weight:753.75
InChIKey: GOWMOJKFENPSNW-UHFFFAOYSA-N
SMILES: O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC5CCN(CC5)C6=CC7=C(C(N(C8CCC(NC8=O)=O)C7=O)=O)C=C6
Biological Activity: PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50<10 nM in MDA-MB-231 cell. PROTAC PARP1 degrader-2 inhibits the cell viability of MDA-MB-436 with an IC50 <100 nM[1].
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PROTAC PARP1 degrader-2 | PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50<10 nM in MDA-MB-231 cell. PROTAC PARP1 degrader-2 inhibits the cell viability of MDA-MB-436 with an IC50 <100 nM. | |||||||||||||||||||||
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