PROTAC PARP1 degrader-2
PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50<10 nM in MDA-MB-231 cell. PROTAC PARP1 degrader-2 inhibits the cell viability of MDA-MB-436 with an IC50 <100 nM.
(Pink: PARP ligand (HY-160937); Blue: VHL ligand (HY-W998262); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 2923686-62-6
- Formula: C38H37F2N9O6
- Molecular Weight:753.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
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VHL |
Chemical Information
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CAS No. 2923686-62-6
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Molecular Weight 753.75
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Formula C38H37F2N9O6
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SMILES
O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC5CCN(CC5)C6=CC7=C(C(N(C8CCC(NC8=O)=O)C7=O)=O)C=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)