2925087-92-7
Chemical Structure
CRBN ligand-741
- CAS No.: 2925087-92-7
- Formula:C14H13N3O4
- Molecular Weight:287.28
IUPAC Name: 7-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-1-methyl-1H-indole-5-carboxylic acid
InChIKey: LQJCSQXNNINONC-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=2C=CN(C2C(=C1)N3C(=O)NC(=O)CC3)C
Biological Activity: CRBN ligand-741 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-741 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-741 | CRBN ligand-741 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-741 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords