2936619-43-9
Chemical Structure
Zastaprazan citrate
Synonym(s): JP-1366 citrate
- CAS No.: 2936619-43-9
- Formula:C22H26N4O.xC6H8O7
- Molecular Weight:362.47 (free base)
SMILES: O=C(CC(C(O)=O)(CC(O)=O)O)O.O=C(N1CCC1)C2=CN3C(C)=C(C)N=C3C(NCC4=C(C)C=CC=C4C)=C2.[x]
Biological Activity: Zastaprazan (JP-1366) citrate is a Proton pump inhibitor and potent potassium-competitive acid blocker. Zastaprazan citrate can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease[1][2].
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Zastaprazan citrate | 99.86% | Zastaprazan (JP-1366) citrate is a Proton pump inhibitor and potent potassium-competitive acid blocker. Zastaprazan citrate can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease. | ||||||||||||||||||||
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- [1]. Oh JH, et al. Randomized, Double-Blind, Active-Controlled Phase 3 Study to Evaluate Efficacy and Safety of Zastaprazan Compared With Esomeprazole in Erosive Esophagitis. Am J Gastroenterol. 2025 Feb 1;120(2):353-361. [Content Brief]
- [2]. Jeongmin Kim, et al. Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof. WO2018008929A1. 2018-01-11.
Keywords