2966790-70-3
2966790-70-3
Chemical Structure
MT-44
- CAS No.: 2966790-70-3
- Formula:C26H23N5O4
- Molecular Weight:469.49
InChIKey: YKJVGXLOKNUKIQ-XHLNEMQHSA-N
SMILES: COC1=CC=C2OC(C3=CC=C4N=C(OC4=C3)N)=C/C(C2=C1)=N\C5=CC=CC=C5NC(CCN)=O
Biological Activity: MT-44 is a highly selective and potent mTOR inhibitor with an IC50 of 49.4 nM. MT-44 can inhibit cancer cells proliferation, migration and invasion. MT-44 can induce cells apoptosis and ROS production and cause G2/M phase arrest. MT-44 can activate the cGAS/STING pathway. MT-44 can be used for the research of cancer, such as triple-negative breast cancer[1].
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MT-44 | MT-44 is a highly selective and potent mTOR inhibitor with an IC50 of 49.4 nM. MT-44 can inhibit cancer cells proliferation, migration and invasion. MT-44 can induce cells apoptosis and ROS production and cause G2/M phase arrest. MT-44 can activate the cGAS/STING pathway. MT-44 can be used for the research of cancer, such as triple-negative breast cancer. | |||||||||||||||||||||
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References
Keywords
