2969172-58-3
Chemical Structure
JD-13
- CAS No.: 2969172-58-3
- Formula:C25H32N4O3
- Molecular Weight:436.55
InChIKey: YWPFUPOYHXXEKB-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(N2N=C(C)C3=C2CC(C)(C)CC3=O)C=C1NC45CCC(CC4)(CC5)O)N
Biological Activity: JD-13 is a HPV-1 inhibitor and anti-proliferative agent against cancer cells. JD-13 downregulates the expression of HSV-1 DNA polymerase-related genes UL30 and UL42, and inhibits viral replication. JD-13 induces apoptosis (apoptosis) in colorectal cancer cells and suppresses their colony formation. JD-13 can be applied to the research of herpes simplex virus infection and related diseases including colorectal cancer, lung cancer, esophageal cancer and breast cancer[1][2].
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JD-13 | JD-13 is a HPV-1 inhibitor and anti-proliferative agent against cancer cells. JD-13 downregulates the expression of HSV-1 DNA polymerase-related genes UL30 and UL42, and inhibits viral replication. JD-13 induces apoptosis (apoptosis) in colorectal cancer cells and suppresses their colony formation. JD-13 can be applied to the research of herpes simplex virus infection and related diseases including colorectal cancer, lung cancer, esophageal cancer and breast cancer. | |||||||||||||||||||||
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References
- [1]. Liu Kaisheng, et al. Novel multi-effect benzamide compound and its preparation method, use method and application. CN116554105A. 2023-04-26.
- [2]. Xiong Y, et al. Mechanical properties of T-joints of offshore floating photovoltaic structure in marine environment[J]. Journal of Constructional Steel Research, 2026, 245: 110509.
