2987726-27-0
2987726-27-0
Chemical Structure
STAT3-IN-9
- CAS No.: 2987726-27-0
- Formula:C22H21N3O4
- Molecular Weight:391.42
IUPAC Name: 1-(7-((3,5-dimethoxyphenyl)amino)-5-(1-methyl-1H-pyrazol-5-yl)benzofuran-2-yl)ethan-1-one
InChIKey: PWYYKSMCHFQAGF-UHFFFAOYSA-N
SMILES: COC1=CC(NC2=CC(C3=CC=NN3C)=CC4=C2OC(C(C)=O)=C4)=CC(OC)=C1
Biological Activity: STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1].
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STAT3-IN-9 | STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase. | |||||||||||||||||||||
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