2999646-13-6

Sirt1/2-IN-4 Chemical Structure
2999646-13-6

Chemical Structure

Sirt1/2-IN-4

  • CAS No.: 2999646-13-6
  • Formula:C21H20N4O3S2
  • Molecular Weight:440.54

InChIKey: CNBCIGYQUBSQAF-UHFFFAOYSA-N

SMILES: O=S(NC1=CC(SC2=NNC=N2)=C(C3=C1C=CC=C3)O)(C4=C(C)C(C)=C(C)C=C4)=O

Biological Activity: Sirt1/2-IN-4 (compound PS3) is a triple inhibitor of SIRT1/2/3 with IC50s of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respsectivley. Sirt1/2-IN-4 completely blocks p53 deacetylation, with potential anti-cancer activity[1].

Cat. No. Product Name Purity Description Pricing
HY-155729 		Sirt1/2-IN-4 Sirt1/2-IN-4 (compound PS3) is a triple inhibitor of SIRT1/2/3 with IC50s of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respsectivley. Sirt1/2-IN-4 completely blocks p53 deacetylation, with potential anti-cancer activity.
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