2999661-74-2

PARP-1-IN-13 Chemical Structure
2999661-74-2

Chemical Structure

PARP-1-IN-13

  • CAS No.: 2999661-74-2
  • Formula:C20H17N5O2S
  • Molecular Weight:391.45

InChIKey: YRQHBYGJPZJJEZ-SSDVNMTOSA-N

SMILES: O=C1NC(C2=CC=C(/C=N/NC(NCC)=S)C=C2)=NC3=C1OC4=C3C=CC=C4

Biological Activity: PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM). PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway[1].

Cat. No. Product Name Purity Description Pricing
HY-155122 		PARP-1-IN-13 PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM). PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway.
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