PARP-1-IN-13
PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM). PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway.
For research use only. We do not sell to patients.
- CAS No.: 2999661-74-2
- Formula: C20H17N5O2S
- Molecular Weight:391.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
26 nM (PARP-1)[1]
Chemical Information
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CAS No. 2999661-74-2
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Molecular Weight 391.45
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Formula C20H17N5O2S
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SMILES
O=C1NC(C2=CC=C(/C=N/NC(NCC)=S)C=C2)=NC3=C1OC4=C3C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP-1-IN-13 Related Classifications
HY-155122 Related Classifications
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