3010895-53-8
3010895-53-8
Chemical Structure
CYP2C19-IN-1
- CAS No.: 3010895-53-8
- Formula:C26H26N2O6S
- Molecular Weight:494.56
IUPAC Name: (3aR,8aS)-2-(6-phenylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
InChIKey: CJIIKXVGUILPKR-UHFFFAOYSA-N
SMILES: O=S(CC1=CC=C2C=C(C3=CC(N(C(N4)=O)C=CC4=O)=CC(C(C)(C)C)=C3OC)C=CC2=C1)(O)=O
Biological Activity: CYP2C19-IN-1 (compound 20d) is a potent CYP2C19 inhibitor, possessing no hepatotoxicity and ames toxicity. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) with a Ki value of 6.16 µM. CYP2C19-IN-1 can be used in study of anti-ZIKV[1].
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CYP2C19-IN-1 | CYP2C19-IN-1 (compound 20d) is a potent CYP2C19 inhibitor, possessing no hepatotoxicity and ames toxicity. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) with a Ki value of 6.16 µM. CYP2C19-IN-1 can be used in study of anti-ZIKV. | |||||||||||||||||||||
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References
Keywords
