3010940-08-3
Chemical Structure
NS2B/NS3-IN-2
- CAS No.: 3010940-08-3
- Formula:C24H21N3O5S
- Molecular Weight:463.51
IUPAC Name: 5-amino-1-((4-ethoxyphenyl)sulfonyl)-1H-pyrazol-3-yl [1,1'-biphenyl]-4-carboxylate
InChIKey: VHEJYZYHDWSAAG-UHFFFAOYSA-N
SMILES: O=S(C(C=C1)=CC=C1OCC)(N2N=C(C=C2N)OC(C3=CC=C(C=C3)C4=CC=CC=C4)=O)=O
Biological Activity: NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 µM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1].
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NS2B/NS3-IN-2 | 98.10% | NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 µM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate. | ||||||||||||||||||||
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Keywords