3010940-08-3
3010940-08-3
Chemical Structure
NS2B/NS3-IN-2
- CAS No.: 3010940-08-3
- Formula:C24H21N3O5S
- Molecular Weight:463.51
IUPAC Name: 5-amino-1-((4-ethoxyphenyl)sulfonyl)-1H-pyrazol-3-yl [1,1'-biphenyl]-4-carboxylate
InChIKey: VHEJYZYHDWSAAG-UHFFFAOYSA-N
SMILES: O=S(C(C=C1)=CC=C1OCC)(N2N=C(C=C2N)OC(C3=CC=C(C=C3)C4=CC=CC=C4)=O)=O
Biological Activity: NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 µM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NS2B/NS3-IN-2 | 98.10% | NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 µM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-134910SID-852843 -
Similarity Score 0.53
![Di(pyridin-2-yl) [1,1'-biphenyl]-4,4'-dicarboxylate Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112157.gif)
HY-W112157Di(pyridin-2-yl) [1,1'-biphenyl]-4,4'-dicarboxylate -
Similarity Score 0.51
HY-119304GW-406381 -
Similarity Score 0.50
HY-103083RGPR40 agonist 4 (Standard) -
Similarity Score 0.49
HY-15877BTB06584 -
Similarity Score 0.49
![5'-Phenyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w586834.gif)
HY-W5868345'-Phenyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid -
Similarity Score 0.48
HY-157023RCB16007 -
Similarity Score 0.48
HY-145230FGFR2-IN-1 -
Similarity Score 0.47
![2'-(Phenyldiazenyl)-[1,1':4',1"-terphenyl]-4,4"-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112697.gif)
HY-W1126972'-(Phenyldiazenyl)-[1,1':4',1"-terphenyl]-4,4"-dicarboxylic acid -
Explore the MedChemAI to find more analogs
![Di(pyridin-2-yl) [1,1'-biphenyl]-4,4'-dicarboxylate Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112157.gif)
![5'-Phenyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w586834.gif)
![2'-(Phenyldiazenyl)-[1,1':4',1"-terphenyl]-4,4"-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112697.gif)
