3018825-60-7
3018825-60-7
Chemical Structure
LRRK2-IN-21
- CAS No.: 3018825-60-7
- Formula:C17H19F3N6O2
- Molecular Weight:396.37
InChIKey: DVQWRJICPNPVFF-JOYOIKCWSA-N
SMILES: CC1=NN(C(N2)=C1OC[C@@H]3COC[C@H]3NC4=NC2=NC=C4C(F)(F)F)C5CC5
Biological Activity: LRRK2-IN-21 is a selective, blood-brain barrier-permeable LRRK2 kinase inhibitor with an IC50 of 0.35 nM. LRRK2-IN-21 inhibits TTK kinase with an IC50 of 70 nM. LRRK2-IN-21 is applicable to the research of Parkinson's disease[1].
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LRRK2-IN-21 | LRRK2-IN-21 is a selective, blood-brain barrier-permeable LRRK2 kinase inhibitor with an IC50 of 0.35 nM. LRRK2-IN-21 inhibits TTK kinase with an IC50 of 70 nM. LRRK2-IN-21 is applicable to the research of Parkinson's disease. | |||||||||||||||||||||
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References
Keywords
