3023019-93-1
3023019-93-1
Chemical Structure
KH-259
- CAS No.: 3023019-93-1
- Formula:C20H25N3O2
- Molecular Weight:339.43
IUPAC Name: N-hydroxy-4-((4-(1-phenylethyl)piperazin-1-yl)methyl)benzamide
InChIKey: ZHVQXJZQHWNCES-UHFFFAOYSA-N
SMILES: CC(N1CCN(CC2=CC=C(C(NO)=O)C=C2)CC1)C3=CC=CC=C3
Biological Activity: KH-259 (compound 1) is a potent, selective and CNS-penetrant HDAC6 inhibitor, with an IC50 of 0.26 μM. KH-259 has antidepressant effects in mice through the inhibition of HDAC6 in the brain. KH-259 can be used for neurodegenerative diseases research[1].
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KH-259 | KH-259 (compound 1) is a potent, selective and CNS-penetrant HDAC6 inhibitor, with an IC50 of 0.26 μM. KH-259 has antidepressant effects in mice through the inhibition of HDAC6 in the brain. KH-259 can be used for neurodegenerative diseases research. | |||||||||||||||||||||
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References
Keywords
