3024545-79-4

CDK7-IN-26 Chemical Structure
3024545-79-4

Chemical Structure

CDK7-IN-26

  • CAS No.: 3024545-79-4
  • Formula:C22H22FN6OPS
  • Molecular Weight:468.49

InChIKey: DHZKWPMYADCRCR-KBPBESRZSA-N

SMILES: O=P(C)(C1=C(C=CC2=C1NC=C2C3=NC(N[C@H]4C[C@H](F)CNC4)=NC5=C3SC=C5)C#N)C

Biological Activity: CDK7-IN-26 (compound 36) is an orally active CDK7 inhibitor (IC50: 7.4 nM). CDK7-IN-26 potently inhibits the growth of triple-negative breast cancer (TNBC) cell line-derived xenograft (CDX) tumors in vivo and inhibits MDA-MB-453 cells in vitro with an IC50 of 0.15 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-157210 		CDK7-IN-26 CDK7-IN-26 (compound 36) is an orally active CDK7 inhibitor (IC50: 7.4 nM). CDK7-IN-26 potently inhibits the growth of triple-negative breast cancer (TNBC) cell line-derived xenograft (CDX) tumors in vivo and inhibits MDA-MB-453 cells in vitro with an IC50 of 0.15 μM.
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